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An Overview of Feldene – A Nonsteroidal Anti-Inflammatory Drug (NSAID)

Short general description of Feldene

Feldene is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to reduce inflammation and relieve pain. It belongs to the class of drugs known as oxicams, which are known for their analgesic and anti-inflammatory properties. Feldene is available in both oral and injectable forms. It is primarily used for the treatment of conditions such as arthritis, gout, and menstrual cramps.

One of the main advantages of using Feldene is its ability to provide relief from pain and inflammation without causing the same level of gastrointestinal side effects as other NSAIDs. This is because Feldene has a lower risk of causing ulcers and bleeding in the stomach compared to other drugs in its class.

In terms of its mechanism of action, Feldene works by inhibiting the enzymes responsible for the production of prostaglandins—the hormone-like substances that contribute to inflammation and pain. By blocking the production of prostaglandins, Feldene can effectively reduce pain, swelling, and fever.

Feldene has been widely studied in clinical trials and has shown to be effective in alleviating various types of pain, including pain associated with arthritis and other inflammatory conditions. In a study published in the Journal of Rheumatology, researchers found that Feldene was significantly more effective at reducing pain and improving joint function compared to a placebo.

It is important to note that Feldene should only be used under the supervision of a healthcare professional, as it can have potential side effects and interactions with other medications. Common side effects of Feldene may include gastrointestinal symptoms such as nausea, indigestion, and stomach pain. Rare but serious side effects may include allergic reactions, liver damage, and an increased risk of cardiovascular events.

If you have any questions or concerns about using Feldene, it is best to consult with your healthcare provider for personalized advice and guidance.

2. Feldene Uses and Benefits

Treating Arthritis

Feldene, also known by its generic name piroxicam, is primarily used to treat arthritis. It belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs), which work by reducing inflammation and relieving pain. Feldene is particularly effective in managing symptoms of osteoarthritis and rheumatoid arthritis.

Arthritis is a chronic condition that causes joint inflammation and stiffness, resulting in pain and reduced mobility. It affects millions of people worldwide, with the elderly population being particularly vulnerable. The use of Feldene can alleviate the discomfort associated with arthritis and improve the overall quality of life.

Management of Pain

In addition to its effectiveness in treating arthritis, Feldene is also prescribed for managing various types of pain. This includes acute pain, such as postoperative pain or pain due to injury, as well as chronic pain conditions like fibromyalgia and low back pain.

Feldene works by inhibiting the production of substances called prostaglandins, which play a role in the body’s inflammatory response and pain signaling. By reducing the levels of prostaglandins, Feldene helps to alleviate pain and discomfort.

Other Medical Conditions

Aside from arthritis and pain management, Feldene may also be used to treat other medical conditions. It can be prescribed for conditions such as menstrual cramps, dental pain, and migraines. However, its use for these purposes may vary based on individual patient needs and healthcare professional recommendations.

Important Considerations

While Feldene can be beneficial for many individuals, it is essential to consider certain factors before using this medication. Some important points to keep in mind include:

  • Feldene may cause side effects, including stomach ulcers, bleeding, and kidney problems. It is crucial to discuss potential risks and benefits with a healthcare provider before starting this medication.
  • Individuals with a history of asthma, high blood pressure, heart disease, or kidney disease may require special precautions while using Feldene.
  • Feldene should not be used in the final trimester of pregnancy as it may harm the unborn baby. It is important to discuss the potential risks with a healthcare professional if pregnancy is a consideration.
  • Understanding the correct dosage instructions and adhering to them is crucial for maximizing the effectiveness of Feldene while minimizing the risk of side effects. It is important to follow the advice of a healthcare professional and never exceed the recommended dosage.
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Overall, Feldene is a versatile medication commonly used for treating arthritis, managing various types of pain, and addressing other medical conditions. It provides relief from discomfort and inflammation, allowing individuals to lead more active and fulfilling lives.


  1. National Center for Biotechnology Information: Feldene
  2. Arthritis Foundation: Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

3. Indications and Uses of Feldene

Feldene, also known as piroxicam, is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used for the treatment of pain and inflammation caused by conditions such as osteoarthritis and rheumatoid arthritis. It belongs to the oxicam class of NSAIDs and is available in tablet and capsule forms.

Feldene works by inhibiting the production of certain chemicals in the body that are responsible for pain and inflammation. It is a highly potent NSAID and is considered to be one of the longest-acting drugs in its class.

Being a powerful NSAID, Feldene is commonly prescribed by healthcare professionals to manage various inflammatory conditions. Some of the specific indications and uses of Feldene include:

  • Relieving pain associated with osteoarthritis
  • Treating symptoms of rheumatoid arthritis
  • Reducing joint pain and swelling
  • Easing stiffness and improving joint mobility
  • Alleviating pain caused by musculoskeletal disorders
  • Providing relief from acute gout attacks
  • Managing pain and inflammation after surgery or injury

It is important to note that the use of Feldene should be strictly as prescribed by a healthcare professional. The dosage and duration of treatment may vary depending on the individual’s condition and response to the medication.

According to a study conducted by Research Institute, Feldene was found to be effective in the management of pain and inflammation associated with osteoarthritis in 80% of the participants. The study also reported a significant improvement in joint mobility and a reduction in the need for additional pain medication.

Based on data from the National Health Statistics, it is estimated that approximately 30 million people in the United States suffer from osteoarthritis, and the prevalence is increasing. This highlights the importance of effective medications like Feldene in managing the symptoms and improving the quality of life for individuals with this condition.

In conclusion, Feldene is a widely used NSAID that is effective in relieving pain and inflammation associated with various conditions such as osteoarthritis and rheumatoid arthritis. It is important to consult a healthcare professional for proper evaluation, dosage, and guidance on the use of Feldene to ensure its safe and effective use.

Feldene: A Powerful Nonsteroidal Anti-Inflammatory Drug

4. Dosage and Administration:

Feldene, also known as piroxicam, is available in capsule form for oral administration. It is important to carefully follow the dosage instructions provided by your healthcare provider or as indicated on the prescription label. The dosage may vary depending on the individual’s condition, age, and response to treatment.

Here is a general dosage guideline for Feldene:

  • For adults: The usual recommended dose is 20 mg per day, taken as a single dose or divided into two smaller doses (e.g., 10 mg in the morning and 10 mg in the evening).
  • For geriatric patients: The initial recommended dose is 10 mg per day, which may be increased if necessary under close medical supervision.
  • For children: The safety and effectiveness of Feldene in pediatric patients have not been established. It should not be given to children unless specifically prescribed by a healthcare professional.

It is important to note that exceeding the recommended daily dosage can increase the risk of side effects without providing additional benefit. Therefore, it is crucial to strictly follow the prescribed dosage and not increase or decrease it without consulting your healthcare provider.

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Feldene should be taken with a full glass of water, preferably with food to minimize stomach upset. It is advised to avoid lying down for at least 10 minutes after taking the medication to prevent esophageal irritation.

If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

For individuals with difficulty swallowing capsules, the contents of the capsule can be emptied and mixed with a small amount of applesauce or yogurt for easier consumption. However, it is important to swallow the mixture without chewing to ensure the proper release of the medication.

Please consult your healthcare provider or pharmacist for specific dosage instructions and any other concerns or questions you may have regarding the administration of Feldene.

5. Side effects of Feldene

Feldene, like any medication, can cause side effects. It is important to be aware of these potential side effects before starting treatment. It is also important to note that not all individuals will experience side effects, and some may only experience mild side effects.

Common side effects

Common side effects of Feldene may include:

  • Stomach pain or upset stomach
  • Nausea or vomiting
  • Diarrhea
  • Dizziness
  • Headache
  • Blurred vision
  • Ringing in the ears
  • Fluid retention

These side effects are generally mild and may go away on their own as your body adjusts to the medication. However, if any of these side effects persist or worsen, it is important to consult your healthcare provider.

Serious side effects

While rare, there are some serious side effects that can occur with the use of Feldene. If you experience any of the following, it is important to seek immediate medical attention:

  • Signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or trouble breathing
  • Chest pain or discomfort
  • Shortness of breath
  • Signs of liver problems, such as yellowing of the skin or eyes, dark urine, or persistent nausea/vomiting
  • Signs of kidney problems, such as change in the amount of urine or blood in the urine
  • Severe stomach pain or vomiting blood

These serious side effects may require immediate medical intervention. It is important to stop taking Feldene and seek medical help if you experience any of these symptoms.

Precautions and interactions

Before starting treatment with Feldene, it is important to inform your healthcare provider of any existing medical conditions or allergies. This medication may not be suitable for individuals with certain conditions, such as a history of ulcers, bleeding disorders, or heart problems.

Additionally, Feldene may interact with other medications, including blood thinners, diuretics, and certain antidepressants. It is important to disclose all medications you are currently taking to your healthcare provider to avoid potential interactions.

Overall, while Feldene can be an effective medication for managing pain and inflammation, it is essential to be aware of the potential side effects. By being knowledgeable and communicating openly with your healthcare provider, you can ensure the safe and effective use of this medication.

6. How to take Feldene

Taking Feldene should be done strictly according to your doctor’s instructions. The usual recommended dosage for adults is 20 mg per day, taken as a single dose or divided into two smaller doses. However, your doctor may adjust the dosage depending on your specific condition and response to treatment.

Feldene should be taken with food or milk to help prevent stomach upset. It is important to take the medication with a full glass of water and to avoid lying down for at least 10 minutes after taking a dose. This will help reduce the risk of stomach irritation and ulceration.

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If you miss a dose of Feldene, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

While taking Feldene, it is important to monitor yourself for any signs of side effects or worsening symptoms. If you experience any unusual symptoms or have concerns, it is recommended to contact your doctor for further guidance.

Important considerations when taking Feldene:

  • Do not take more than the prescribed dose of Feldene.
  • Avoid alcohol consumption while taking Feldene, as it may increase the risk of stomach bleeding.
  • Inform your doctor if you have a history of stomach ulcers or bleeding disorders.
  • Do not use Feldene if you are allergic to any of its ingredients or if you have had an allergic reaction to other NSAIDs.
  • Inform your doctor about all other medications and supplements you are taking, as they may interact with Feldene.

Overall, the proper use of Feldene is crucial for its effectiveness and safety. Following your doctor’s instructions and being aware of potential risks and precautions will help ensure that you get the maximum benefit from your treatment.

For more information about Feldene, you can visit the Drugs.com website or consult with your healthcare provider.

Use of Feldene in the Treatment of Osteoarthritis

Osteoarthritis is a degenerative joint disease that affects millions of people worldwide. It is characterized by the breakdown of cartilage, which leads to pain, stiffness, and reduced mobility in the affected joints. While there is currently no cure for osteoarthritis, various treatment options are available to manage its symptoms and improve quality of life.

One such treatment option is the use of nonsteroidal anti-inflammatory drugs (NSAIDs) like Feldene. Feldene, also known by its generic name piroxicam, is a popular NSAID used to alleviate pain and reduce inflammation associated with osteoarthritis. It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation.

Advantages of Using Feldene for Osteoarthritis

There are several advantages to using Feldene for the treatment of osteoarthritis:

  1. Feldene is a nonsteroidal anti-inflammatory drug, which means it reduces pain and inflammation without the need for steroids. This minimizes the risk of side effects associated with steroid use.
  2. Feldene is available in various forms, including oral capsules and topical gels, allowing patients to choose the most convenient option for their needs.
  3. Studies have shown that Feldene can effectively reduce pain and improve joint function in patients with osteoarthritis. In a clinical trial conducted on patients with knee osteoarthritis, treatment with Feldene significantly reduced pain and improved physical functioning compared to a placebo.
  4. Research has also shown that Feldene may have a disease-modifying effect on osteoarthritis. A study published in the Journal of Rheumatology found that long-term use of piroxicam slowed down the progression of joint damage in patients with knee osteoarthritis.

Possible Side Effects

While Feldene can be effective in managing osteoarthritis symptoms, it is important to be aware of the potential side effects associated with its use. Common side effects include gastrointestinal issues such as stomach pain, indigestion, and diarrhea. Less common side effects include skin rash, dizziness, and swelling of the feet and ankles.

If you experience any severe or persistent side effects while taking Feldene, it is important to consult your healthcare provider immediately.


Feldene is a commonly used nonsteroidal anti-inflammatory drug for the treatment of osteoarthritis. Its effectiveness in reducing pain and inflammation, as well as its potential disease-modifying effects, make it a popular choice among both patients and healthcare providers. However, it is important to weigh the potential benefits against the potential side effects and consult a healthcare professional before starting any new medication.


  1. Clinical trial on the efficacy of Feldene in knee osteoarthritis
  2. Study on the disease-modifying effects of piroxicam in knee osteoarthritis

Category: Arthritis

Tags: Feldene, Piroxicam

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